Modulation of beta1-integrins on hemopoietic progenitor cells after allergen challenge in asthmatic subjects.

@article{Catalli2008ModulationOB,
  title={Modulation of beta1-integrins on hemopoietic progenitor cells after allergen challenge in asthmatic subjects.},
  author={Adriana E Catalli and Jennifer V Thomson and Irene M Babirad and Mylinh T Duong and Tracey M Doyle and Karen J. Howie and Paul Newbold and Richard Craggs and Martyn Foster and Gail M Gauvreau and Paul M O'Byrne and Roma Sehmi},
  journal={The Journal of allergy and clinical immunology},
  year={2008},
  volume={122 4},
  pages={
          803-810
        }
}
BACKGROUND Mobilization of hemopoietic progenitor cells from the bone marrow (BM) is a feature of inflammatory asthmatic responses. Understanding the mechanisms regulating progenitor cell mobilization and trafficking to the peripheral circulation might be important for the development of effective asthma therapies. OBJECTIVE We investigated the role of adhesion molecules in the mobilization of hemopoietic progenitor cells from the BM during an allergen-induced asthmatic response. METHODS BM… CONTINUE READING
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