Modulation of beta-lactam resistance in Staphylococcus aureus by catechins and gallates.

@article{Stapleton2004ModulationOB,
  title={Modulation of beta-lactam resistance in Staphylococcus aureus by catechins and gallates.},
  author={Paul D Stapleton and Saroj J Shah and J. Christopher Anderson and Yukihiko Hara and J M Hamilton-miller and Peter W. Taylor},
  journal={International journal of antimicrobial agents},
  year={2004},
  volume={23 5},
  pages={462-7}
}
Aqueous extracts of Japanese green tea (Camellia sinensis) are able to reverse beta-lactam resistance in methicillin-resistant Staphylococcus aureus (MRSA). We have attributed the capacity to reverse oxacillin resistance in the homogeneous PBP2a producer BB568 and in EMRSA-16 to (-)-epicatechin gallate (ECG) and (-)-catechin gallate (CG). Minimum inhibitory… CONTINUE READING