Modulation of apoptosis in intestinal lymphocytes by a probiotic bacteria in Crohn's disease.

Abstract

Apoptosis of active T lymphocytes constitutes a major control mechanism of immune homeostasis and tolerance. In Crohn's disease, abnormal activation of mucosal T lymphocytes against enteric bacteria is the key event triggering intestinal inflammation. Resistance of lymphocytes to apoptosis has been proposed as the pathogenetic defect. We examined the… (More)

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Cite this paper

@article{Carol2006ModulationOA, title={Modulation of apoptosis in intestinal lymphocytes by a probiotic bacteria in Crohn's disease.}, author={M{\'o}nica Carol and Natalia Borruel and Mar{\'i}a Antol{\'i}n and Marta Llopis and Francesc Casellas and Francisco Guarner and Juan-R Malagelada}, journal={Journal of leukocyte biology}, year={2006}, volume={79 5}, pages={917-22} }