Modulation of anti-IgM-induced B cell apoptosis by Bcl-xL and CD40 in WEHI-231 cells. Dissociation from cell cycle arrest and dependence on the avidity of the antibody-IgM receptor interaction.

Abstract

The demise of B cell progenitors expressing functional IgM receptors for self appears to be the main mechanism by which B cell tolerance is accomplished. The genetic mechanisms that regulate the death process during this critical step of B cell development are still poorly understood. We have studied the regulation of apoptosis in WEHI-231 lymphoma cells… (More)

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@article{Merino1995ModulationOA, title={Modulation of anti-IgM-induced B cell apoptosis by Bcl-xL and CD40 in WEHI-231 cells. Dissociation from cell cycle arrest and dependence on the avidity of the antibody-IgM receptor interaction.}, author={R. Merino and Didier A.M. Grillot and Philip L. Simonian and Subramanian Muthukkumar and William C. Fanslow and Subbarao Bondada and G. N{\'u}{\~n}ez}, journal={Journal of immunology}, year={1995}, volume={155 8}, pages={3830-8} }