Modulation of anthracycline activity in canine mammary tumour cells in vitro by medroxyprogesterone acetate.

@article{Pagnini2000ModulationOA,
  title={Modulation of anthracycline activity in canine mammary tumour cells in vitro by medroxyprogesterone acetate.},
  author={Ugo Pagnini and Salvatore Florio and Pietro Lombardi and Danila d'Angelo and Luigi Avallone and Marilena Galdiero and Giuseppe Iovane and Giampaolo Tortora and Giuseppe Pagnini},
  journal={Research in veterinary science},
  year={2000},
  volume={69 3},
  pages={255-62}
}
Failure of chemotherapy with anthracyclines as a result of drug resistance and toxicity is a major problem in the clinical management of neoplasia. The aim of the present study was to evaluate the activity of medroxyprogesterone acetate (MPA) as a chemosensitiser on anthracycline cytotoxicity. The study investigated whether such an effect could be related… CONTINUE READING