Modulation of angiogenic potential of collagen matrices by covalent incorporation of heparin and loading with vascular endothelial growth factor.

Abstract

One of the prominent shortcomings of matrices for tissue engineering is their poor ability to support angiogenesis. We report here on experiments to enhance the angiogenic properties of collagen matrices. Our aim is to achieve this goal by covalently incorporating heparin into collagen matrices and by physically immobilizing angiogenic vascular endothelial… (More)

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@article{Steffens2004ModulationOA, title={Modulation of angiogenic potential of collagen matrices by covalent incorporation of heparin and loading with vascular endothelial growth factor.}, author={G. C. M. Steffens and C. Yao and Pascale Pr{\'e}vel and Marta P Markowicz and Paula Schenck and E. M. Noah and Nobert Pallua}, journal={Tissue engineering}, year={2004}, volume={10 9-10}, pages={1502-9} }