Modulation of alveolar macrophage-driven fibroblast proliferation by alternative macrophage mediators.

@article{Bitterman1986ModulationOA,
  title={Modulation of alveolar macrophage-driven fibroblast proliferation by alternative macrophage mediators.},
  author={Peter Bitterman and Mark D Wewers and Stephen I. Rennard and S A Adelberg and Ronald G. Crystal},
  journal={The Journal of clinical investigation},
  year={1986},
  volume={77 3},
  pages={700-8}
}
Tissue fibrosis results, in part, from an interaction between growth regulatory molecules released by mononuclear phagocytes and fibroblasts. In the chronic interstitial lung disorders, alveolar macrophages, the mononuclear phagocytes of the lung, are known to spontaneously release two growth factors for fibroblasts, fibronectin and alveolar macrophage… CONTINUE READING