Modulation of alkaline phosphatase activity in KB cells by hyperosmolality and prednisolone: Effect on enzyme inhibition by phosphate

Abstract

A striking reduction in alkaline phosphatase activity occurs when KB cells (originally derived from a human nasopharyngeal carcinoma) are grown in hyperosmolar media and/or with prednisolone. This reduction is accompanied by the transition of the activity from predominantly heat-labile to heat-stable and by changes in susceptibility to inhibition by… (More)
DOI: 10.1007/BF02615339

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