Modulation of a presynaptic hyperpolarization-activated cationic current (I(h)) at an excitatory synaptic terminal in the rat auditory brainstem.

@article{Cuttle2001ModulationOA,
  title={Modulation of a presynaptic hyperpolarization-activated cationic current (I(h)) at an excitatory synaptic terminal in the rat auditory brainstem.},
  author={Matthew F. Cuttle and Zolt{\'a}n Ruszn{\'a}k and Adrian Y. C. Wong and Steven E. Owens and Ian D. Forsythe},
  journal={The Journal of physiology},
  year={2001},
  volume={534 Pt 3},
  pages={733-44}
}
1. A hyperpolarization-activated non-specific cation current, I(h), was examined in bushy cell bodies and their giant presynaptic terminals (calyx of Held). Whole-cell patch clamp recordings were made using an in vitro brain slice preparation of the cochlear nucleus and the superior olivary complex. The aim was to characterise I(h) in identified cell bodies and synaptic terminals, to examine modulation by presynaptic cAMP and to test for modulatory effects of I(h) activation on synaptic… CONTINUE READING