Modulation of Transforming Growth Factor β‐1 Gene Expression by Interleukin‐12

@article{Wilkinson2000ModulationOT,
  title={Modulation of Transforming Growth Factor $\beta$‐1 Gene Expression by Interleukin‐12},
  author={Wilkinson and Aung and Wu and Toossi},
  journal={Scandinavian Journal of Immunology},
  year={2000},
  volume={52}
}
  • Wilkinson, Aung, +1 author Toossi
  • Published 2000
  • Biology, Medicine
  • Scandinavian Journal of Immunology
The interaction of cytokines and their net balance with regard to macrophage activation (or deactivation) and immune stimulation (or suppression), ultimately determines the success of host‐immune response at sites of active infection. A regulatory role for interleukin (IL)‐12 in production of transforming growth factor (TGF)‐β1 has been suggested, however, remains controversial. In this study, we analyzed the effect of IL‐12 on TGF‐β1 expression in the human lines, K562 and A549, and in primary… Expand
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  • Biology, Medicine
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  • 2002
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