Modulation of T-cell function by gliomas.

@article{Roszman1991ModulationOT,
  title={Modulation of T-cell function by gliomas.},
  author={Thomas L. Roszman and Lucinda H. Elliott and William H. Brooks},
  journal={Immunology today},
  year={1991},
  volume={12 10},
  pages={370-4}
}
Patients with primary intracranial tumors (gliomas) exhibit a profound decrease in immunity, the mechanism of which has, until recently, remained obscure. Here Thomas Roszman, Lucinda Elliott and William Brooks reveal that T cells obtained from these patients exhibit defects in interleukin 2 secretion and in expression of the high-affinity IL-2 receptor and they discuss the role played by immunosuppressive factors produced by gliomas in inducing these defects. 

From This Paper

Topics from this paper.
89 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 89 extracted citations

Similar Papers

Loading similar papers…