Modulation of Renin-Angiotensin System May Slow Conversion from Mild Cognitive Impairment to Alzheimer's Disease.

@article{Wharton2015ModulationOR,
  title={Modulation of Renin-Angiotensin System May Slow Conversion from Mild Cognitive Impairment to Alzheimer's Disease.},
  author={Whitney Wharton and Felicia C. Goldstein and Liping Zhao and Kyle Steenland and Allan I. Levey and Ihab Hajjar},
  journal={Journal of the American Geriatrics Society},
  year={2015},
  volume={63 9},
  pages={
          1749-56
        }
}
OBJECTIVES To assess the effect of modulation of the renin-angiotensin system (RAS) on conversion to Alzheimer's disease (AD) and cognitive decline in people with mild cognitive impairment (MCI) and the effect of the permeability of the blood-brain barrier (BBB) and race on the potential relationship between the RAS and AD. DESIGN Analysis of data from AD centers funded by the National Alzheimer's Coordinating Center, National Institute on Aging. SETTING Alzheimer's Disease Centers… CONTINUE READING
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