Modulation of Opiate-Related Signaling Molecules in Morphine-Dependent Conditioned Behavior: Conditioned Place Preference to Morphine Induces CREB Phosphorylation

@article{Morn2010ModulationOO,
  title={Modulation of Opiate-Related Signaling Molecules in Morphine-Dependent Conditioned Behavior: Conditioned Place Preference to Morphine Induces CREB Phosphorylation},
  author={Jos{\'e} A. Mor{\'o}n and Srinivas Gullapalli and Chirisse Taylor and Achla Gupta and Ivone Gomes and Lakshmi A Devi},
  journal={Neuropsychopharmacology},
  year={2010},
  volume={35},
  pages={955-966}
}
Opiate addiction is a chronic, relapsing behavioral disorder where learned associations that develop between the abused opiate and the environment in which it is consumed are brought about through Pavlovian (classical) conditioning processes. However, the signaling mechanisms/pathways regulating the mechanisms that underlie the responses to opiate-associated cues or the development of sensitization as a consequence of repeated context-independent administration of opiates are unknown. In this… CONTINUE READING

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