Modulation of Neurotransmitter Release in the Basal Ganglia of the Rat Brain by Dynorphin Peptides ZHI-BING YOU, MARIO HERRERA-MARSCHITZ, and LARS TERENIUS

Abstract

Microinjection studies have found that although dynorphin peptides decrease dopamine release in the rat basal ganglia, the nonselective opiate antagonist naloxone produces the opposite effect. To investigate the contribution of the dynorphin pathways to a tonic modulation of dopamine release, a microdialysis study was undertaken, with probes implanted in… (More)

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