Modulation of Neuronal Survival Factor MEF2 by Kinases in Parkinson’s Disease

@inproceedings{Yin2012ModulationON,
  title={Modulation of Neuronal Survival Factor MEF2 by Kinases in Parkinson’s Disease},
  author={Yue Yin and Hua She and Wenming Li and Qian Yang and Shuzhong Guo and Zixu Mao},
  booktitle={Front. Physio.},
  year={2012}
}
Parkinson's disease (PD) is the second most common neurodegenerative disorder due to selective death of neurons in the substantia nigra pars compacta. The cause of cell death remains largely unknown. Myocyte enhancer factor 2 (MEF2) is a group of transcriptional factors required to regulate neuronal development, synaptic plasticity, as well as survival. Recent studies show that MEF2 functions are regulated in multiple subcellular organelles and suggest that dysregulation of MEF2 plays essential… CONTINUE READING

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