Modulation of NMDA receptor responsiveness by neurotransmitters, drugs and chemical modification.

@article{Reynolds1990ModulationON,
  title={Modulation of NMDA receptor responsiveness by neurotransmitters, drugs and chemical modification.},
  author={Ian Jeffrey Reynolds},
  journal={Life sciences},
  year={1990},
  volume={47 20},
  pages={
          1785-92
        }
}
The NMDA receptor is intimately involved an a wide range of pathophysiological processes in the mammalian brain, including epilepsy and ischemia-induced neurodegeneration. The widespread distribution of NMDA receptors places almost every area of the brain at risk from NMDA receptor over-activity. However, it is clear that the central nervous system can function effectively without imminent danger of self-destruction. The focus of this review is the processes that control NMDA receptor… CONTINUE READING
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