Modulation of NK cell lytic function by endometrial secretory factors: potential role in endometriosis.

@article{Somigliana1996ModulationON,
  title={Modulation of NK cell lytic function by endometrial secretory factors: potential role in endometriosis.},
  author={Edgardo Somigliana and Paola Vigan{\'o} and B Gaffuri and Massimo Candiani and Mauro Busacca and Anna M. Di Blasio and Michele Vignali},
  journal={American journal of reproductive immunology},
  year={1996},
  volume={36 5},
  pages={295-300}
}
PROBLEM Development and progression of endometriosis have been suggested to be related to a defect of NK cells in the ability to eliminate endometrial fragments regurgitated with menstrual debris in ectopic sites. However, it has not been clarified yet whether the origin of this defect has to be attributed to an intrinsic alteration of NK cell population or to a consequence of the environmental system. The present study was designed to evaluate whether soluble factors of endometrial origin… CONTINUE READING
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