Modulation of Micro RNA Expression and Osteoblast Differentiation by Nanotopography.

@article{Sartori2018ModulationOM,
  title={Modulation of Micro RNA Expression and Osteoblast Differentiation by Nanotopography.},
  author={Elisa Mattias Sartori and Osvaldo Magro-Filho and Daniela B Silveira Mendonça and Xiang Pan Li and Jianping Fu and Gustavo Borges de Mendonça},
  journal={The International journal of oral & maxillofacial implants},
  year={2018},
  volume={33 2},
  pages={
          269-280
        }
}
PURPOSE This study evaluated the expression pattern of micro RNAs (miRNAs) on a surface with nanotopography compared with a smooth surface (control). MATERIALS AND METHODS Human mesenchymal stem cells (hMSCs) were plated on different surfaces and compared at 3, 7, and 14 days for alkaline phosphatase (ALP) activity, expression of genes (osterix [OSX], runt-related transcription factor 2 [RUNX2], bone morphogenetic protein 2 [BMP2], and ALP), and expression of miRNAs. Western blot was also… CONTINUE READING
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