Modulation of MHC antigen expression by viruses and oncogenes.

@article{Maudsley1991ModulationOM,
  title={Modulation of MHC antigen expression by viruses and oncogenes.},
  author={D. J. Maudsley and John D. Pound},
  journal={Immunology today},
  year={1991},
  volume={12 12},
  pages={429-31}
}
It is becoming increasingly clear that regulation of MHC antigen expression by viruses and oncogenes, leading to either immune evasion or autoimmunity, is widespread and important in disease. At a recent meeting*, which brought together workers interested in tumour immunology, viral infection and the MHC, a number of mechanisms for the regulation of MHC antigen expression were revealed and the importance of balanced expression of MHC gene products to effective immunity was underlined.