Modulation of LPS-, PHA- and M. tuberculosis-mediated cytokine production by pentoxifylline and thalidomide.

@article{Crevel2000ModulationOL,
  title={Modulation of LPS-, PHA- and M. tuberculosis-mediated cytokine production by pentoxifylline and thalidomide.},
  author={Reinout van Crevel and Alieke G. Vonk and Mihai G Netea and Bart Jan Kullberg and Jos W M van der Meer},
  journal={European cytokine network},
  year={2000},
  volume={11 4},
  pages={574-9}
}
Pentoxifylline and thalidomide have been used to downregulate the production of TNF-alpha in several disease entities including mycobacterial infections and autoimmune disorders. These drugs inhibit the production of TNF-alpha by different mechanisms, but little is known about possible synergism and modulation of other cytokines. Pentoxifylline and… CONTINUE READING