Modulation of Kv1.5 currents by Src tyrosine phosphorylation: potential role in the differentiation of astrocytes.

Abstract

Using biophysical techniques, we previously have implicated outwardly rectifying potassium currents in the proliferation of cultured spinal cord astrocytes and have demonstrated that delayed rectifier potassium currents (I(Kd)), in particular, are upregulated on entry into the cell cycle and downregulated with cell cycle exit and differentiation. In the… (More)

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@article{Macfarlane2000ModulationOK, title={Modulation of Kv1.5 currents by Src tyrosine phosphorylation: potential role in the differentiation of astrocytes.}, author={S N Macfarlane and Harold Sontheimer}, journal={The Journal of neuroscience : the official journal of the Society for Neuroscience}, year={2000}, volume={20 14}, pages={5245-53} }