Modulation of Intestinal Epithelial Glycocalyx Development by Human Milk Oligosaccharides and Non‐Digestible Carbohydrates

@article{Kong2019ModulationOI,
  title={Modulation of Intestinal Epithelial Glycocalyx Development by Human Milk Oligosaccharides and Non‐Digestible Carbohydrates},
  author={Chunli Kong and M. Elderman and Lianghui Cheng and B. D. de Haan and A. Nauta and P. de Vos},
  journal={Molecular Nutrition & Food Research},
  year={2019},
  volume={63}
}
  • Chunli Kong, M. Elderman, +3 authors P. de Vos
  • Published 2019
  • Chemistry, Medicine
  • Molecular Nutrition & Food Research
  • Scope The epithelial glycocalyx development is of great importance for microbial colonization. Human milk oligosaccharides (hMOs) and non‐digestible carbohydrates (NDCs) may modulate glycocalyx development. Methods and results The effects of hMOs and NDCs on human gut epithelial cells (Caco2) are investigated by quantifying thickness and area coverage of adsorbed albumin, heparan sulfate (HS), and hyaluronic acid (HA) in the glycocalyx. Effects of hMOs (2′‐FL and 3‐FL) and NDCs [inulins with… CONTINUE READING
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