Modulation of GABA-mediated inhibition in rat cerebellar slices by benzodiazepine receptor ligands.

@article{Hussain1991ModulationOG,
  title={Modulation of GABA-mediated inhibition in rat cerebellar slices by benzodiazepine receptor ligands.},
  author={S. Hussain and Jeff Bagust and R A Ward and Colin R. Gardner and Robert J. Walker},
  journal={General pharmacology},
  year={1991},
  volume={22 5},
  pages={
          907-15
        }
}
10 Citations
GABAA Receptors of Cerebellar Granule Cells in Culture: Interaction with Benzodiazepines
TLDR
It is shown how rat cerebellar granule cells in culture may be a useful model for studying new benzodiazepine site agonists based on the pharmacological separation of diazepam-sensitive α1 β2/3 γ2 receptors from those which are diazepAM-insensitive and contain the α6 subunit.

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TLDR
It is concluded that this α-subunit is part of a cerebellar receptor subtype, selective for Rol5-4513 (refs 17, 18), an antagonist of alcohol-induced motor incoordination and ataxia, and photoaffinity-labelled with benzodiazepines.
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TLDR
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TLDR
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