Modulation of Dengue virus infection in human cells by alpha, beta, and gamma interferons.

@article{Diamond2000ModulationOD,
  title={Modulation of Dengue virus infection in human cells by alpha, beta, and gamma interferons.},
  author={Michael S Diamond and Thomas G. Roberts and Dianna Edgil and Betty F Lu and Joel Ernst and Eva Harris},
  journal={Journal of virology},
  year={2000},
  volume={74 11},
  pages={4957-66}
}
A role for interferon (IFN) in modulating infection by dengue virus (DV) has been suggested by studies in DV-infected patients and IFN receptor-deficient mice. To address how IFN modulates DV type 2 infection, we have assayed IFN-alpha, -beta, and -gamma for the ability to enhance or diminish antibody-independent and antibody-dependent cell infection using a competitive, asymmetric reverse transcriptase-mediated PCR (RT-PCR) assay that quantitates positive and negative strands of viral RNA, a… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 136 extracted citations

Similar Papers

Loading similar papers…