Modulation of Cytokine Production and Transcription Factors Activities in Human Jurkat T Cells by Thymol and Carvacrol.

@article{Gholijani2015ModulationOC,
  title={Modulation of Cytokine Production and Transcription Factors Activities in Human Jurkat T Cells by Thymol and Carvacrol.},
  author={Nasser Gholijani and Marjan Gharagozloo and Fathollah Kalantar and Amin Ramezani and Zahra Amirghofran},
  journal={Advanced pharmaceutical bulletin},
  year={2015},
  volume={5 Suppl 1},
  pages={
          653-60
        }
}
PURPOSE Thymol and carvacrol, two main components of thyme, have shown anti-inflammatory effects. The aim of this study was to assess the effects of these components on Jurkat leukemia cells as an in vitro T cell model and their molecular mechanisms of activity. METHODS Cells were cultured in the presence of components and subsequently stimulated with phorbol-12-myristate-13-acetate (PMA)/calcium ionophore for evaluating interleukin (IL)-2 and interferon (IFN)-γ production. The activation of… CONTINUE READING

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-8 OF 8 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 32 REFERENCES

Modulation of cell proliferation, survival and gene expression by rage and tlr signaling in cells of the innate and adaptive immune response: Role of p38 mapk and nf-kb

MC Medeiros, SC Frasnelli, S Bastos Ade, SR Orrico, C Jr.Rossa
  • J Appl Oral Sci 2014;22(3):185-93
  • 2014
VIEW 1 EXCERPT

Antiinflammatory, anti arthritis and analgesic effect of ethanolic extract of whole plant of merremia emarginata burm

T Purushoth Prabhu, P Panneerselvam, R Vijaykumar, W Clement Atlee, S. Balasubramanian
  • F. Cent Europ J Exp Biol
  • 2012
VIEW 1 EXCERPT