Modulation of Cellular Proliferation Alters Glutamine Transport and Metabolism in Human Hepatoma Cells

@article{Bode1994ModulationOC,
  title={Modulation of Cellular Proliferation Alters Glutamine Transport and Metabolism in Human Hepatoma Cells},
  author={B. Bode and W. Souba},
  journal={Annals of Surgery},
  year={1994},
  volume={220},
  pages={411–424}
}
OBJECTIVE The authors determined the effects of growth inhibition on glutamine transport and metabolism in human hepatoma cells. SUMMARY BACKGROUND DATA Hepatoma cells exhibit markedly higher (10- to 30-fold) glutamine uptake than normal human hepatocytes, via a disparate transporter protein with a higher affinity for glutamine. Currently, little is known about the effects of growth arrest on glutamine transport and metabolism in hepatoma cells. METHODS The authors determined proliferation… Expand
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