Modulation of Ca2+ cycling in cardiac myocytes by arachidonic acid.

@article{Damron1993ModulationOC,
  title={Modulation of Ca2+ cycling in cardiac myocytes by arachidonic acid.},
  author={Derek S Damron and Mason Bond},
  journal={Circulation research},
  year={1993},
  volume={72 2},
  pages={376-86}
}
It is believed that inotropic agents exert their effects in cardiac muscle via a modulation of Ca2+ cycling; however, the involvement of phospholipase activation and the biochemical pathways participating in inotropic responsiveness remain unclear. The aim of the current study was to determine whether arachidonic acid and/or eicosanoids participate in inotropic responses by modulating Ca2+ cycling in cardiac myocytes. Experiments were performed with populations of freshly isolated, fura-2… CONTINUE READING

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