Modulation by interferons of HLA antigen, high-molecular-weight melanoma associated antigen, and intercellular adhesion molecule 1 expression by cultured melanoma cells with different metastatic potential.

@article{Maio1989ModulationBI,
  title={Modulation by interferons of HLA antigen, high-molecular-weight melanoma associated antigen, and intercellular adhesion molecule 1 expression by cultured melanoma cells with different metastatic potential.},
  author={Michele Maio and Beena Gulwani and Jerome A. Langer and Robert S. Kerbel and Gregory J Duigou and Paul B Fisher and Soldano Ferrone},
  journal={Cancer research},
  year={1989},
  volume={49 11},
  pages={2980-7}
}
The effect of leukocyte (IFN-alpha), fibroblast (IFN-beta), and immune (IFN-gamma) interferon and/or mezerein on the expression of HLA antigens and melanoma-associated antigens by the melanoma cell line MeWo and its metastatic variant MeM 50-10 was investigated, since this information may contribute to our understanding of the molecular mechanism(s) underlying the metastatic process and of the role of cell differentiation and growth suppression in the antigenic changes induced by interferon… CONTINUE READING