Modulation by divalent cations of the current generated by vasopressin in facial motoneurons.

  title={Modulation by divalent cations of the current generated by vasopressin in facial motoneurons.},
  author={Stefano Alberi and Michel L Dubois-Dauphin and J. J. Dreifuss and Mario Raggenbass},
  journal={Brain research},
  volume={624 1-2},
Vasopressin generates a voltage-gated, sodium-dependent current in facial motoneurons in brainstem slices. Reducing the extracellular calcium concentration from 2 to 0.01 mM caused a 30 to 120% increase in the amplitude of this current. Lowering extracellular magnesium also enhanced it, but less efficiently. In the physiological solution, the response of facial neurons to vasopressin is thus partially blocked. Increasing extracellular calcium was without effect. Current-voltage curves indicate… CONTINUE READING

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