Modulating the interaction of CXCR4 and CXCL12 by low-molecular-weight heparin inhibits hepatic metastasis of colon cancer

Abstract

Liver metastasis is the major obstacle for prolonging the survival of colon cancer patients. Low-molecular-weight heparin (LMWH), a common drug for venous thromboembolism, has displayed beneficial effects in improving the survival of cancer patients, though the mechanism remains unclear. This study aimed to investigate the effects of LMWH on hepatic… (More)
DOI: 10.1007/s10637-010-9578-0

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@article{Ma2010ModulatingTI, title={Modulating the interaction of CXCR4 and CXCL12 by low-molecular-weight heparin inhibits hepatic metastasis of colon cancer}, author={Lixin Ma and Haiquan Qiao and Changjun He and Qian Yang and Chun Cheung and J. R. Kanwar and Xueying Sun}, journal={Investigational New Drugs}, year={2010}, volume={30}, pages={508-517} }