Modulating iNOS-uncoupling: a new therapeutic avenue to tackle reperfusion-injury?

@article{Juni2011ModulatingIA,
  title={Modulating iNOS-uncoupling: a new therapeutic avenue to tackle reperfusion-injury?},
  author={Rio P. Juni and An L. Moens},
  journal={Journal of molecular and cellular cardiology},
  year={2011},
  volume={50 5},
  pages={924}
}
Okazaki et al. [1] reported in issue 50 (3) of the Journal of Molecular and Cellular Cardiology that iNOS is upregulated in the heart of diabetic rat and that inhibition of inducible nitric oxide synthase (iNOS)-uncoupling by tetrahydrobiopterin decreases oxidative/nitrosative stress and increases the bioavailability of nitric oxide which may provide… CONTINUE READING