Modulated expression of adhesion molecules and galectin-1: role during mesenchymal stromal cell immunoregulatory functions.

@article{Najar2010ModulatedEO,
  title={Modulated expression of adhesion molecules and galectin-1: role during mesenchymal stromal cell immunoregulatory functions.},
  author={Mehdi Najar and Gordana Raicevic and Hicham Id Boufker and Basile Stamatopoulos and C{\'e}cile De Bruyn and Nathalie Meuleman and Dominique Bron and Michel Toungouz and Laurence Lagneaux},
  journal={Experimental hematology},
  year={2010},
  volume={38 10},
  pages={922-32}
}
OBJECTIVE As mesenchymal stromal cells (MSCs) have been proposed as a tool for management or prevention of graft-vs-host disease, we investigated their immunoregulatory properties, their expression of adhesion molecules and galectin-1, and the impact of environment context on these functions. MATERIALS AND METHODS The effects of MSCs on T-cell proliferation were analyzed using carboxyfluorescein diacetate N-succinimidyl ester labeling. We evaluated the expression of adhesion molecules and… CONTINUE READING