Modularity in PPI Networks : Characteristics of Existing Networks and Models of Evolution

@inproceedings{YeModularityIP,
  title={Modularity in PPI Networks : Characteristics of Existing Networks and Models of Evolution},
  author={Min Ye and Xiuwei Zhang and Bernard M. E. Moret}
}
Networks are often used to represent interactions in biology. Databases store many such networks, observed or inferred. Generative models have been proposed for various biological networks; for PPI networks, current models are based on duplication and divergence (D&D): a node is duplicated and inherits some subset of the connections of the original node. An early finding about biological networks was modularity: these networks present a higher-level structure consisting of well connected… CONTINUE READING

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