Modular stop and go extraction tips with stacked disks for parallel and multidimensional Peptide fractionation in proteomics.

Abstract

Proteome complexity necessitates protein or peptide separation prior to analysis. We previously described a pipet-tip based peptide micropurification system named StageTips (STop and Go Extraction Tips), which consists of a very small disk of membrane-embedded separation material. Here, we extend this approach in several dimensions by stacking disks… (More)

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