Modular stop and go extraction tips with stacked disks for parallel and multidimensional Peptide fractionation in proteomics.


Proteome complexity necessitates protein or peptide separation prior to analysis. We previously described a pipet-tip based peptide micropurification system named StageTips (STop and Go Extraction Tips), which consists of a very small disk of membrane-embedded separation material. Here, we extend this approach in several dimensions by stacking disks… (More)


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