Modular organization of a Cdc6-like protein from the crenarchaeon Sulfolobus solfataricus.

@article{Felice2004ModularOO,
  title={Modular organization of a Cdc6-like protein from the crenarchaeon Sulfolobus solfataricus.},
  author={Mariarita De Felice and Luca Giangiuseppe Esposito and Biagio Pucci and Mariarosaria De Falco and Giuseppe Manco and Mos{\'e} Rossi and F. Pisani},
  journal={The Biochemical journal},
  year={2004},
  volume={381 Pt 3},
  pages={645-53}
}
In the present paper, we report that a Cdc6 (cell-division control)-like factor from the hyperthermophilic crenarchaeon Sulfolobus solfataricus (referred to as SsoCdc6-2) has a modular organization of its biological functions. A reliable model of the SsoCdc6-2 three-dimensional structure was built up, based on the significant sequence identity with the Pyrobaculum aerophylum Cdc6 (PaeCdc6), whose crystallographic structure is known. This allowed us to design two truncated forms of SsoCdc6-2… CONTINUE READING

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Biochemical characterization of a Cdc6-like protein from the crenarchaeon Sulfolobus solfataricus

M. De Felice, L. Esposito, +4 authors F. M. Pisani
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B. R. Berquist, S. DasSarma
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