Modular cell biology: retroactivity and insulation

@article{DelVecchio2008ModularCB,
  title={Modular cell biology: retroactivity and insulation},
  author={Domitilla Del Vecchio and A. J. Ninfa and Eduardo Sontag},
  journal={Molecular Systems Biology},
  year={2008},
  volume={4},
  pages={161 - 161}
}
Modularity plays a fundamental role in the prediction of the behavior of a system from the behavior of its components, guaranteeing that the properties of individual components do not change upon interconnection. Just as electrical, hydraulic, and other physical systems often do not display modularity, nor do many biochemical systems, and specifically, genetic networks. Here, we study the effect of interconnections on the input–output dynamic characteristics of transcriptional components… 

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...

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