Modular and Versatile Spatial Functionalization of Tissue Engineering Scaffolds through Fiber-Initiated Controlled Radical Polymerization.

@article{Harrison2015ModularAV,
  title={Modular and Versatile Spatial Functionalization of Tissue Engineering Scaffolds through Fiber-Initiated Controlled Radical Polymerization.},
  author={Rachael H. Harrison and Joseph A. M. Steele and Robert Clark Chapman and Adam J Gormley and Lesley W Chow and Muzamir M. Mahat and Lucia Podhorska and Robert G Palgrave and David J Payne and Shehan P Hettiaratchy and Iain E Dunlop and Molly M Stevens},
  journal={Advanced functional materials},
  year={2015},
  volume={25 36},
  pages={
          5748-5757
        }
}
Native tissues are typically heterogeneous and hierarchically organized, and generating scaffolds that can mimic these properties is critical for tissue engineering applications. By uniquely combining controlled radical polymerization (CRP), end-functionalization of polymers, and advanced electrospinning techniques, a modular and versatile approach is introduced to generate scaffolds with spatially organized functionality. Poly-ε-caprolactone is end functionalized with either a polymerization… CONTINUE READING
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