Modular analysis of gene expression data with R

  title={Modular analysis of gene expression data with R},
  author={G{\'a}bor Cs{\'a}rdi and Zolt{\'a}n Kutalik and Sven Bergmann},
  volume={26 10},
SUMMARY Large sets of data, such as expression profiles from many samples, require analytic tools to reduce their complexity. The Iterative Signature Algorithm (ISA) is a biclustering algorithm. It was designed to decompose a large set of data into so-called 'modules'. In the context of gene expression data, these modules consist of subsets of genes that exhibit a coherent expression profile only over a subset of microarray experiments. Genes and arrays may be attributed to multiple modules and… CONTINUE READING
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