Modular Total Synthesis in Reticular Chemistry.

  title={Modular Total Synthesis in Reticular Chemistry.},
  author={Liang Feng and Kun-Yu Wang and Xiu‐Liang Lv and Tian-Hao Yan and Jian‐Rong Li and Hong‐Cai Zhou},
  journal={Journal of the American Chemical Society},
The idea of modularity in organic total synthesis has promoted the construction of diverse targeted natural products by varying the building blocks and assembly sequences. Yet its utilization has been mainly limited to the synthesis of molecular compounds based on covalent bonds. In this work, we expand the conceptual scope of modular synthesis into framework materials, which bridges metal- and covalent organic frameworks (MOFs and COFs) hierarchically in reticular chemistry. While the assembly… 

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