Modular Closed-Loop Control of Diabetes

  title={Modular Closed-Loop Control of Diabetes},
  author={Stephen D. Patek and Lalo Magni and Eyal Dassau and Christopher W. Karvetski and Chiara Toffanin and Giuseppe De Nicolao and Simone Del Favero and Marc D. Breton and Chiara Dalla Man and Elisabeth Renard and Howard C. Zisser and Francis J. Doyle and Claudio Cobelli and Boris P. Kovatchev},
  journal={IEEE Transactions on Biomedical Engineering},
Modularity plays a key role in many engineering systems, allowing for plug-and-play integration of components, enhancing flexibility and adaptability, and facilitating standardization. In the control of diabetes, i.e., the so-called “artificial pancreas,” modularity allows for the step-wise introduction of (and regulatory approval for) algorithmic components, starting with subsystems for assured patient safety and followed by higher layer components that serve to modify the patient's basal rate… CONTINUE READING