Modular 3D printed lab-on-a-chip bio-reactor for the biochemical energy cascade of microorganisms

@article{Podwin2017Modular3P,
  title={Modular 3D printed lab-on-a-chip bio-reactor for the biochemical energy cascade of microorganisms},
  author={A. Podwin and J. Dziuban},
  journal={Journal of Micromechanics and Microengineering},
  year={2017},
  volume={27},
  pages={104004}
}
The paper presents the sandwiched polymer 3D printed lab-on-a-chip bio-reactor for the biochemical energy cascade of microorganisms. Euglenas and yeast were separately and simultaneously cultured for 10 d in the chip. As a result of the experiments, euglenas, light-initialized and nourished by CO2—a product of ethanol fermentation handled by yeast—generated oxygen, based on the photosynthesis process. The presence of oxygen in the bio-reactor was confirmed by the colorimetric method—a… Expand
A 3D Printed Membrane-Based Gas Microflow Regulator for On-Chip Cell Culture
A miniature 3D printed membrane-based gas microflow regulator which delivers gaseous media to on-chip cell cultures is presented in this paper. The device uses a polydimethylosiloxane (PDMS) membraneExpand
3D-printed miniaturized fluidic tools in chemistry and biology.
TLDR
This work focuses on the development/rapid prototyping and manufacturing of MAS with 3DP, and application dependent challenges in engineering designs and choice of the polymeric materials and provides an exhaustive background to the applications of 3DP in biology and chemistry. Expand

References

SHOWING 1-10 OF 35 REFERENCES
"Bio-switch Chip" Based on Nanostructured Conducting Polymer and Entrapped Enzyme.
We report a switchable biochip strategy where enzymes were entrapped in conducting polymer layers and the enzymatic reaction of the entrapped enzymes was controlled in real-time via electricalExpand
Glucose level determination with a multi-enzymatic cascade reaction in a functionalized glass chip.
TLDR
This work shows the functionalization of the interior of microfluidic glass chips with poly(2-hydroxyethyl methacrylate) polymer brushes as anchors for co-immobilizing of the enzymes glucose-oxidase and horseradish peroxidases, which can be used for improving the efficiency of glucose sensors. Expand
Inkjet 3D Printing – Studies on Applicability for Lab-on-a-chip Technique
Abstract Three-dimensional (3D) printing has the potential to transform science and technology by creating bespoke, low-cost appliances that previously required dedicated facilities in order to beExpand
3D Printed Electrophoretic Lab-on-chip for DNA Separation
Abstract In this paper we present for the first time inkjet 3D printed lab-on-a-chip for DNA analyse by on-chip gel electrophoresis. Separation of 50÷800 bp DNA ladder was successfully performed.Expand
Biofuels from Microalgae
TLDR
Developments in microalgal cultivation and downstream processing are expected to further enhance the cost‐effectiveness of the biofuel from microalgae strategy. Expand
Prospects of low temperature co-fired ceramic (LTCC) based microfluidic systems for point-of-care biosensing and environmental sensing
Low temperature co-fired ceramic (LTCC) based microfluidic devices are being developed for point-of-care biomedical and environmental sensing to enable personalized health care. This article reviewsExpand
Photosynthetic biocathode enhances the power output of a sediment-type microbial fuel cell
Conventional microbial fuel cells (MFCs) consist of biological anodes and abiotic cathodes separated by a proton-exchange membrane. The abiotic cathode usually catalyses the reduction of oxygen toExpand
The low temperature co-fired ceramics (LTCC) chip for polymerase chain reaction (PCR) application
The DNA (deoxyribonucleic acid) amplification chip made of DP951 (from DuPont) ceramics consists of a microchamber, internal and external metallization. The external metallization is used forExpand
3D printed microfluidic devices with integrated valves.
TLDR
3D printed valves are successfully demonstrated for up to 800 actuations and use a custom resin formulation tailored for low non-specific protein adsorption. Expand
DNA amplification on a PDMS–glass hybrid microchip
In this paper, the development of a hybrid polydimethylsiloxane (PDMS)?glass microchip for PCR (polymerase chain reaction) was reported. A novel temperature control strategy was applied for preciseExpand
...
1
2
3
4
...