Modifying the product pattern of Clostridium acetobutylicum

@article{Lehmann2011ModifyingTP,
  title={Modifying the product pattern of Clostridium acetobutylicum},
  author={D{\"o}rte Lehmann and Daniel H{\"o}nicke and A. Ehrenreich and M. Schmidt and D. Weuster-Botz and H. Bahl and Tina L{\"u}tke-Eversloh},
  journal={Applied Microbiology and Biotechnology},
  year={2011},
  volume={94},
  pages={743-754}
}
  • Dörte Lehmann, Daniel Hönicke, +4 authors Tina Lütke-Eversloh
  • Published 2011
  • Chemistry, Medicine
  • Applied Microbiology and Biotechnology
  • Clostridial acetone–butanol–ethanol (ABE) fermentation is a natural source for microbial n-butanol production and regained much interest in academia and industry in the past years. Due to the difficult genetic accessibility of Clostridium acetobutylicum and other solventogenic clostridia, successful metabolic engineering approaches are still rare. In this study, a set of five knock-out mutants with defects in the central fermentative metabolism were generated using the ClosTron technology… CONTINUE READING
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