Modified vaccinia Ankara: potential as an alternative smallpox vaccine.

  title={Modified vaccinia Ankara: potential as an alternative smallpox vaccine.},
  author={Lewis Mccurdy and Brenda D. Larkin and Julie E. Martin and Barney S. Graham},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  volume={38 12},
Despite the declaration of smallpox eradication in 1980, the existence of variola stockpiles and the threat of bioterrorism demand that immunity to smallpox through vaccination be maintained. Although the currently available vaccine was used for the most successful medical intervention ever accomplished, it also is associated with side effects that are difficult to accept in a vaccine for a disease that has not been present for >25 years. Herein, we review alternative approaches to maintaining… CONTINUE READING

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