Modified oral food challenge used with sensitization biomarkers provides more real-life clinical thresholds for peanut allergy.

@article{Blumchen2014ModifiedOF,
  title={Modified oral food challenge used with sensitization biomarkers provides more real-life clinical thresholds for peanut allergy.},
  author={Katharina Blumchen and Alena Beder and John Beschorner and Frank Ahrens and Armin Gruebl and Eckard H. Hamelmann and Gesine Hansen and Andrea Heinzmann and Katja Nemat and Bodo Niggemann and Ulrich Wahn and Kirsten Beyer},
  journal={The Journal of allergy and clinical immunology},
  year={2014},
  volume={134 2},
  pages={390-8}
}
BACKGROUND Threshold levels for peanut allergy determined by using oral challenges are important for the food industry with regard to allergen labeling. Moreover, the utility of biological markers in predicting threshold levels is uncertain. OBJECTIVE We sought to use a modified oral food challenge regimen that might determine threshold levels for peanut allergy mimicking a more real-life exposure and to correlate the eliciting dose (ED) and severity of clinical reaction in children with… CONTINUE READING
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