Modified cantilever arrays improve sensitivity and reproducibility of nanomechanical sensing in living cells

@inproceedings{Patil2018ModifiedCA,
  title={Modified cantilever arrays improve sensitivity and reproducibility of nanomechanical sensing in living cells},
  author={Samadhan B. Patil and Rajai M. Al-Jehani and Hashem Etayash and Val{\'e}rian Turb{\'e} and Keren Jiang and Joe Bailey and Walid Al-Akkad and Rania Soudy and Kamaljit Kaur and Rachel A. McKendry and Thomas George Thundat and Joseph Wafula Ndieyira},
  booktitle={Communications Biology},
  year={2018}
}
Mechanical signaling involved in molecular interactions lies at the heart of materials science and biological systems, but the mechanisms involved are poorly understood. Here we use nanomechanical sensors and intact human cells to provide unique insights into the signaling pathways of connectivity networks, which deliver the ability to probe cells to produce biologically relevant, quantifiable and reproducible signals. We quantify the mechanical signals from malignant cancer cells, with 10… CONTINUE READING
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