Modified allergens and their potential to treat allergic disease.

  title={Modified allergens and their potential to treat allergic disease.},
  author={Laurian Jongejan and Ronald van Ree},
  journal={Current allergy and asthma reports},
  volume={14 12},
Allergen-specific immunotherapy is the only treatment of allergic diseases that aims at modifying the underlying immune mechanism. Current protocols are long and at risk of anaphylactic reactions. The main aim of current research is decreasing the risk of side effects and increasing efficacy, in particular targeting reduction of treatment duration. Since the advent of molecular biology, extracts can be replaced by recombinant hypo-allergens, peptides, or fusion proteins. In addition, different… CONTINUE READING

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