Modified ELISPOT technique--highly significant inverse correlation of post-Tx donor-reactive IFNgamma-producing cell frequencies with 6 and 12 months graft function in kidney transplant recipients.

Abstract

BACKGROUND Upcoming trials for immunosuppression minimization and tolerance induction require the development of reliable in vitro assays for monitoring cellular alloimmunity in transplant patients. The IFN-gamma ELISPOT assay represents a promising tool for monitoring alloreactive memory/effector T cells. As T lymphopenia is a common finding during the… (More)

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@article{Nther2006ModifiedET, title={Modified ELISPOT technique--highly significant inverse correlation of post-Tx donor-reactive IFNgamma-producing cell frequencies with 6 and 12 months graft function in kidney transplant recipients.}, author={Bele Johanna N{\"a}ther and Peter Nickel and Gantuja Bold and Franziska Presber and Constanze Schoenemann and Johann Pratschke and Hans - Dieter Volk and Petra Reinke}, journal={Transplant immunology}, year={2006}, volume={16 3-4}, pages={232-7} }