Modifications of arterial phenotype in response to amine oxidase inhibition by semicarbazide.

@article{Mercier2007ModificationsOA,
  title={Modifications of arterial phenotype in response to amine oxidase inhibition by semicarbazide.},
  author={N. Mercier and Khadija El Hadri and Mary J. Osborne-Pellegrin and Johnny Nehm{\'e} and Claudine Perret and Carlos Labat and V{\'e}ronique R{\'e}gnault and J. -M. Daniel Lamaziere and Pascal Challande and Patrick Lacolley and Bruno F{\`e}ve},
  journal={Hypertension},
  year={2007},
  volume={50 1},
  pages={234-41}
}
Semicarbazide-sensitive amine oxidase (SSAO)-deficient mice present no alteration in elastin cross-linking processes and carotid mechanical properties. In contrast, previous studies have shown that SSAO inhibitors induced marked anomalies in arterial structure and function. The aim of the present study was to examine the effect of semicarbazide (SCZ), an efficient SSAO inhibitor, on the arterial phenotype of the carotid artery in relation to modulation of SSAO and lysyl oxidase activities in… CONTINUE READING
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