Modifications of ambulation-increasing effect of morphine and buprenorphine following repeated administration in mice.

Abstract

Interaction of behavioral effects of morphine (10 and 20 mg/kg s. c.) and buprenorphine (0.3 and 1 mg/kg s. c.) were investigated by means of ambulatory activity following repeated administration of either drug in mice. The repeated administration of buprenorphine (1 mg/kg, but not 0.3 mg/kg) total of 5 times at intervals of 3-4 days induced a gradual… (More)

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@article{Asahi1991ModificationsOA, title={Modifications of ambulation-increasing effect of morphine and buprenorphine following repeated administration in mice.}, author={Takehisa Asahi and Hiroshi Kuribara and Satoshi Tadokoro}, journal={Arukoru kenkyu to yakubutsu izon = Japanese journal of alcohol studies & drug dependence}, year={1991}, volume={26 6}, pages={522-30} }