Modification of ubiquitin C-terminal hydrolase L1 by reactive lipid species: role in neural regeneration and diseases of aging

Role of ubiquitin C-terminal hydrolase L1 (UCHL1) in brain function: Ubiquitin is used by a variety of cellular systems to tag proteins for transport to various organelles. There are a number of enzymes in the ubiquitin-proteasome pathway (UPP) that tag abnormally folded proteins with ubiquitin for transport to the proteasome for degradation. UCHL1 is a… (More)